Updated 1 March 2012
Supply of typhoid and hepatitis A/typhoid (combined) vaccines
GlaxoSmithKline (GSK): Typherix® (Vi polysaccharide typhoid vaccine) and Hepatyrix® (combined hepatitis A and typhoid vaccine)
GSK has announced that Typherix® and Hepatyrix® are not currently available. The global supply of these vaccines has been constrained due to a delay in a new manufacturing facility coming on line. GSK has had to concentrate production on critical childhood vaccines as prioritised by the World Health Organization. GSK has updated information relating to the manufacture and supply of these vaccines as follows:
Typherix - GSK expects there will be an out of stock situation from late July 2011 until at least the second quarter of 2014
Hepatyrix – Limited supplies will be available Spring 2012, but once this stock is exhausted, vaccine will be out of stock through to the second quarter of 2014
All queries relating to this situation should be directed to the GSK Customer Contact team on 0808 100 9997, or alternatively your local GSK Travel Health Account Manager.
Sanofi Pasteur MSD: Typhim Vi (Vi polysaccharide typhoid vaccine).
All queries relating to the supply of this product should be directed to the Sanofi Pasteur MSD Customer Operations team on 0800 085 5511, or alternatively your local Sanofi Pasteur MSD Vaccine Territory Manager.
There are currently no supply constraints for hepatitis A vaccine products manufactured by Sanofi Pasteur MSD.
There are currently no supply constraints for Vivotif® or hepatitis A vaccine products manufactured by Crucell.
Typhoid and Hepatitis A
Typhoid and hepatitis A are transmitted through contaminated food and water. Those at higher risk include travellers visiting friends and relatives, young children, long-term travellers, and those exposed to conditions of poor sanitation.
Current vaccines are between 50-80% protective against Salmonella Typhi. Travellers should practise strict food, water and personal hygiene precautions in addition to vaccination (if indicated).
Individual country recommendations for vaccination are available on the NaTHNaC Country Information Pages.